"Painkiller Jane" is a television series that premiered in 2007 and aired for one season on the Sci-Fi Channel (now known as Syfy). The show is based on the comic book character of the same name created by Jimmy Palmiotti and Joe Quesada.

The series follows Jane Vasco (played by Kristanna Loken), a former DEA agent who gains the ability to rapidly heal from injuries after being exposed to a genetic weapon. Jane uses her new abilities to become a vigilante and track down dangerous individuals who pose a threat to society.

As Jane investigates various cases, she is aided by a team of scientists, including Dr. Seth Carpenter (played by Noah Danby) and Riley Jensen (played by Sean Owen Roberts), who work to understand the origins of her powers and develop new technologies to assist her.

The show features a mix of action, drama, and science fiction elements, with Jane encountering a variety of threats, including other individuals with superhuman abilities, bio-engineered creatures, and corrupt government officials. Over the course of the season, Jane must also confront her own past and come to terms with the consequences of her actions.

While "Painkiller Jane" was praised for Loken's performance and its high production values, it struggled with low ratings and was ultimately cancelled after one season. However, the character of Jane has continued to appear in various comic book series and other media.